You can use one domain for both ClickBank and JVZoo affiliate marketing but different pages. Many affiliates successfully promote products from both platforms using the same website with different pages dedicated for each. You should choose a niche that fits the products from both networks. This strategy helps attract a targeted audience. You can create content that reviews or discusses products from both platforms. You must ensure your affiliate links are clearly labeled. Transparency builds trust with your audience. You should also monitor your performance on each platform. This approach allows you to optimize your strategies for better results. Using one domain can be effective for affiliate marketing.