ShareASale can be as profitable as the Amazon Affiliate Program but it depends on your strategy. ShareASale offers a wide range of merchants and products to promote. You can choose products that align with your audience’s interests. Amazon offers a huge variety of products but the commission rates are often lower. ShareASale has higher commission rates for certain programs. You can earn more per sale with ShareASale depending on the merchant you choose. Both programs offer opportunities to make money. The profitability of each program depends on how well you market and promote the products.